Liposome Suspension by Anaglyphic Stereo
Freeze fracture and etching, then viewed by TEM
Sample was prepared by first rapid quenching using jet freezing techniques,
followed by preparation by freeze fracture and teching, followed by transmission
electron microscopy of the replica of the fractured surface. The difference in
angular position was 0° and +2°.
In order to see the 3D stereo effect, it is necessary to have
anaglyphic stereo glasses of the "red/cyan" type.
For best viewing of this analglyphic stereo image, and also, to more easily
acclimate the eyes for this kind of viewing, we recommend a viewing distance,
at least to start, of approximately 3 feet or 1 meter. After the eyes become
acclimated, you can slowly come closer to the screen, moving to the right and
left. If the stereo effect is "lost", then back up until it comes back and
repeat.
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This micrograph demonstrates many of the different features one is likely
to see in actual liposome suspensions including unilamellar, bi-lamellar and
even multilamellar structures. |
Special note: Structure Probe, Inc., via our laboratory
services, offer high quality freeze fracture TEM analytical services. Our
experience spans a roughly ten year period doing these kinds of studies for
clients on a contract or purchase order basis.